Passion Pit’s been off the road for two years while mastermind Michael Angelakos (pictured) worked on getting his life and mental health together, but the electro-pop outfit returns to perform in the city where it all began at House of Blues on Friday. In a new interview with the Independent, Angelakos discusses what’s up with his bipolar condition and decision to perform again despite the rigors of touring. In addition to marking the 10^th anniversary of songs like “Sleepyhead,” the tour offers a chance to hear material from last year’s Tremendous Sea of Love, which is something the singer’s bound to receive from hometown fans.

Other concert options for Friday night include roots-rockers the Felice Brothers stirring up at the Sinclair, Bill Janovitz playing solo (ahead of a new Buffalo Tom album in March) in the Burren’s back room with Mike Gent, and 10,000 Maniacs (with three old members plus violinist Mary Ramsey now their singer for 20 years since the departure of Natalie Merchant) appearing for two shows at City Winery.

Lana Del Rey’s been earning headlines of late around Radiohead’s alleged legal threat over the similarity of her song “Get Free” to “Creep” (it does sound eerily similar until the chorus). Apart from an acapella snippet by request in Chicago, she hasn’t been featuring that song on tour, but there’s sure to be plenty of stylized, narcotic favorites from that California-inspired ingénue (including a heavy dose of her 2012 debut Born to Die) at TD Garden on Saturday.

The same night boasts the annual return of Cracker and Camper Van Beethoven (both conveniently fronted by David Lowery) to the Middle East Downstairs and UK rockers the Wombats at the Paradise Rock Club. And Saturday offers a wicked local bill at Once Ballroom including Goddamn Glenn’s recast Parlour Bells (celebrating their pointed new album Waylaid in the Melee!), another charismatic standout in the rockabilly-edged Diablogato and the band Cujo with Jen Trynin.

A groundswell of great local musicians also team up in the Burren’s back room on late Sunday afternoon and early evening for a third annual fundraiser for Hybrasil drummer Jeff Berlin, who’s battled health issues (event proceeds go to Our Space, Inc., helping teens and children with cancer). Besides a Hybrasil reunion, the bill includes Vapors of Morphine and Club d’elf, with Morphine saxman Dana Colley playing in both (he’s also with d’elf on Friday at the Lizard Lounge), plus the Bow Thayer Band, the Revelations (a gospel vehicle with “Jenny Dee” D’Angora and Andrea Gillis), the Weisstronauts and Jimmy Ryan. And two other Sunday sure shots are the ’90s-fueled rockers the Verve Pipe at City Winery and original Bueno Vista Social Club arranger Juan de Marcos & the Afro-Cuban All Stars in a World Music/CRASHarts show at the Berklee Performance Center.