Brooklyn indie-rocker Lady Lamb, aka Aly Spaltro, sought an intimacy that recalls her roots as a Maine-bred solo performer on new EP Tender Warriors Club and The Living Room Tour, a current acoustic swing of tiny venues. Spaltro steps away from that tour to play the Sinclair on Friday, but you can still expect her to plumb the kind of stark emotional depths that first brought her through Boston.

Jazz of varied hues also kicks off the weekend. Saxophonist/composer and New England Conservatory professor Miguel Zenon, who plays the South End’s Villa Victoria Center for the Arts on Friday, further nods to his Puerto Rican heritage with his decade-plus quartet on Tipico, another gem on a resume that includes being a multi-Grammy nominee and Guggenheim and MacArthur Fellow. Another MacArthur “genius grant” winner, violinist Regina Carter plays tribute to her jazz inspiration Ella Fitzgerald in her program “Simply Ella” at Sanders Theatre the same night. And just across Harvard Square, guitarist John Scofield brings his Country for Old Men quartet ever-anchored by drummer Bill Stewart to the Regattabar on both Friday and Saturday nights.
Saturday offers a rare show at the Plough & Stars by the Trinary System, a rock trio led by guitarist/singer Roger Miller (Mission of Burma, Alloy Orchestra) that promises to cover King Crimson’s “Red” in honor of recently deceased Crimson bassist John Wetton. And Rhode Island blues-rock journeyman Neal Vitullo stokes his guitar with Neal and the Vipers for an early Saturday show at Thunder Road.

And the Grammy Awards aren’t the only thing happening on Sunday. World Music/CRASHarts presents soulful jazz singer Dianne Reeves and her band at the Berklee Performance Center. And postponed from Thursday’s blizzard, the Drive-By Truckers roll into Royale with their politically charged, Southern-rooted rock.